signs and symptoms

Abdominal pain
Nausea and vomiting
Jaundice results from high blood levels of bilirubin. Normally, bilirubin is metabolised in the liver and eliminated through the bile ducts. But a blocked bile duct can cause bilirubin to accumulate in the blood.
Loss of appetite or weight
Jaundice is the most common initial sign of bile duct cancer (cholangiocarcinoma). Other signs and symptoms include:

Enlarged gallbladder
Intense itching (pruritus)
Brown coloured urine
Loss of appetite and weight
White or clay-coloured stools
Fever